Terapia e synuar (trajtimi i q\u00ebllimsh\u00ebm) p\u00ebrfshin ila\u00e7et t\u00eb cilat p\u00ebrdoren p\u00ebr trajtimin e kancerit dhe vepron duke bllokuar mekanizmat specifike t\u00eb qeliz\u00ebs kancerogjene. Dr. Sllavica Kraleva, onkologe radioterapiste n\u00eb qendr\u00ebn p\u00ebr onkologji dhe radiologji n\u00eb spitalin klinik \u201cAcibadem Sistina\u201d, shpjegon se fal\u00eb hulumtimeve\u00a0 t\u00eb gj\u00ebra n\u00eb lidhje me mekanizmat molekulare t\u00eb cilat ndikojn\u00eb n\u00eb krijimin dhe rritjen e qeliz\u00ebs kancerogjene, sot, ky lloj trajtimi \u00ebsht\u00eb nj\u00eb histori e suksesshme e trajtimit t\u00eb disa llojeve t\u00eb kancerit.<\/p>\n

Si ndikon?<\/span><\/p>\n

P\u00ebr t\u00eb kuptuar se si ndikon terapia e synuar para s\u00eb gjithash duhet t\u00eb shpjegohet se si funksionon qeliza kancerogjene.\u00a0 \u00c7do ind dhe \u00e7do organ \u00ebsht\u00eb i p\u00ebrb\u00ebr\u00eb nga qeliza. Qelizat vazhdimisht marrin sinjale n\u00eb lidhje me rritjen e tyre, ndarjen dhe vdekjen e tyre. Shfaqja e k\u00ebtyre sinjaleve brenda qelizave lidhet me gjene dhe proteina t\u00eb ndryshme.\u00a0 Tek qelizat normale dhe t\u00eb sh\u00ebndetshme, \u00e7do sinjal \u00ebsht\u00eb i kontrolluar plot\u00ebsisht.<\/p>\n

N\u00ebse shfaqet \u00e7rregullim i kontrollit p\u00ebr kalimin e sinjalit deri n\u00eb brend\u00ebsi t\u00eb qelizave, shfaqet \u00e7rregullim i mekanizmave t\u00eb cilat jan\u00eb p\u00ebrgjegj\u00ebse p\u00ebr rritjen, shumimin, vdekjen e qelizave\u00a0 dhe shfaqjen e kancerit. Kjo shfaqet si rezultat i ndryshimeve gjenetike (mutacioneve). Terapia e synuar (target) ka p\u00ebr q\u00ebllim ti korrigjoj\u00eb dhe modifikoj\u00eb mesazhet e \u00e7rregullta t\u00eb qelizave kancerogjene, me an\u00eb t\u00eb t\u00eb cilit ngadal\u00ebsohet ose ndalohet rritja e pakontrolluar e tumorit.<\/p>\n

Cili \u00ebsht\u00eb q\u00ebllimi i k\u00ebtij lloj trajtimi?<\/h2>\n

N\u00eb var\u00ebsi t\u00eb p\u00ebrhapjes dhe llojit t\u00eb kancerit, terapia e synuar \u00a0mund t\u00eb p\u00ebrdoret p\u00ebr:<\/p>\n

–\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Ngadal\u00ebsimin e rritjes s\u00eb kancerit<\/p>\n

–\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Shkat\u00ebrrimin e qelizave kancerogjene t\u00eb cilat jan\u00eb p\u00ebrhapur edhe n\u00eb pjes\u00eb t\u00eb tjera t\u00eb trupit<\/p>\n

–\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Reduktimin e simptomave t\u00eb shkaktuara nga kanceri<\/p>\n

–\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Sh\u00ebrimin e plot\u00eb t\u00eb s\u00ebmundjes<\/p>\n

Dallimi nd\u00ebrmjet terapis\u00eb s\u00eb synuar dhe kimioterapis\u00eb<\/h2>\n

Terapia e synuar molekulare ndikon tek qelizat t\u00eb cilat jan\u00eb p\u00ebrgjegj\u00ebse p\u00ebr s\u00ebmundjen kancerogjene\u00a0 dhe nuk i d\u00ebmton qelizat dhe indet e sh\u00ebndetshme. Kimioterapia si nj\u00eb trajtim standard, gjat\u00eb trajtimit t\u00eb kancerit mund\u00ebson shkat\u00ebrrimin e qelizave kancerogjene. Aktiviteti i saj citotoksik\u00a0 mund t\u00eb shkjaktoj\u00eb \u00a0edhe d\u00ebmtimin e qelizave t\u00eb sh\u00ebndetshme t\u00eb cilat kan\u00eb kapacitet p\u00ebr t\u00eb riparuar, ndryshe nga qelizat kancerogjene t\u00eb cilat nuk e kan\u00eb k\u00ebt\u00eb mund\u00ebsi. Ndryshimi nd\u00ebrmjet kimioterapis\u00eb dhe terapis\u00eb s\u00eb synuar, \u00ebsht\u00eb n\u00eb fakt mund\u00ebsia q\u00eb ka terapia e synuar p\u00ebr ti sulmuar vet\u00ebm qelizat kancerogjene, pasi \u00ebsht\u00eb e synuar drejt\u00eb q\u00ebllimeve specifike q\u00eb karakterizojn\u00eb vet\u00ebm qelizat kancerogjene.\u00a0 Si rezultat i k\u00ebsaj dhe efektet \u00a0an\u00ebsore jan\u00eb m\u00eb pak t\u00eb r\u00ebnda n\u00eb krahasim me ato t\u00eb shkaktuara nga kimioterapia. Gjith\u00ebsesi, duhet theksuar se terapia e synuar shpesh p\u00ebrdoret n\u00eb kombinim me kimioterapin\u00eb dhe radioterapin\u00eb, me q\u00ebllim p\u00ebr t\u00eb pasur nj\u00eb trajtim m\u00eb t\u00eb suksessh\u00ebm.<\/p>\n

Si merret terapia e synuar?<\/h2>\n

Terapia e synuar mund t\u00eb merret n\u00eb form\u00eb tabletash apo kapsulash, t\u00eb cilat pacient\u00ebt i marrin n\u00eb kushtet e sht\u00ebpis\u00eb, ose me an\u00eb t\u00eb rrug\u00ebs intravenoze n\u00eb spital.<\/p>\n

Kanceret t\u00eb cilat mund t\u00eb trajtohen me terapi t\u00eb synuar<\/h2>\n

Shumica e kancereve mund t\u00eb trajtohen me terapi t\u00eb synuar: kanceri i gjirit, kanceri metastatik n\u00eb stomak, kanceri metastatik kolorektal (gastrik), kanceri i mushk\u00ebrive, melanoma.<\/p>\n

Efektet an\u00ebsore t\u00eb terapis\u00eb s\u00eb synuar<\/h2>\n

Terapia e synuar tolerohet mir\u00eb dhe nuk shkakton efekte an\u00ebsore tipike t\u00eb cilat jan\u00eb t\u00eb njohura tek kimioterapia, si\u00e7 \u00ebsht\u00eb r\u00ebnia e flok\u00ebve, neveritje dhe t\u00eb vjellat. Ila\u00e7et t\u00eb cilat p\u00ebrfshihen n\u00eb k\u00ebt\u00eb grup, karakterizohen me toksicitet p\u00ebr \u00e7do individ dhe mund t\u00eb shkaktojn\u00eb presion t\u00eb lart\u00eb t\u00eb gjakut, reaksione alergjike proteinuria dhe ndonj\u00ebher\u00eb edhe probleme gastrointestinale.<\/p><\/p>\n","protected":false},"excerpt":{"rendered":"

Terapia e synuar (trajtimi i q\u00ebllimsh\u00ebm) p\u00ebrfshin ila\u00e7et t\u00eb cilat p\u00ebrdoren p\u00ebr trajtimin e kancerit dhe vepron duke bllokuar mekanizmat specifike t\u00eb qeliz\u00ebs kancerogjene. Dr. Sllavica Kraleva, onkologe radioterapiste n\u00eb qendr\u00ebn p\u00ebr onkologji dhe radiologji n\u00eb spitalin klinik \u201cAcibadem Sistina\u201d, shpjegon se fal\u00eb hulumtimeve\u00a0 t\u00eb gj\u00ebra n\u00eb lidhje me mekanizmat molekulare t\u00eb cilat ndikojn\u00eb n\u00eb krijimin dhe rritjen e qeliz\u00ebs kancerogjene, sot, ky lloj trajtimi \u00ebsht\u00eb nj\u00eb histori e suksesshme e trajtimit t\u00eb disa llojeve t\u00eb kancerit.<\/p>\n","protected":false},"author":2,"featured_media":3610,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[367],"tags":[],"doktori":[],"class_list":["post-3611","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kancer-sq"],"acf":[],"_links":{"self":[{"href":"https:\/\/healthacibadem.unet.mk\/wp-json\/wp\/v2\/posts\/3611","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthacibadem.unet.mk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthacibadem.unet.mk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthacibadem.unet.mk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/healthacibadem.unet.mk\/wp-json\/wp\/v2\/comments?post=3611"}],"version-history":[{"count":0,"href":"https:\/\/healthacibadem.unet.mk\/wp-json\/wp\/v2\/posts\/3611\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/healthacibadem.unet.mk\/wp-json\/wp\/v2\/media\/3610"}],"wp:attachment":[{"href":"https:\/\/healthacibadem.unet.mk\/wp-json\/wp\/v2\/media?parent=3611"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthacibadem.unet.mk\/wp-json\/wp\/v2\/categories?post=3611"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthacibadem.unet.mk\/wp-json\/wp\/v2\/tags?post=3611"},{"taxonomy":"doktori","embeddable":true,"href":"https:\/\/healthacibadem.unet.mk\/wp-json\/wp\/v2\/doktori?post=3611"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}